Complex Coacervation in Polyelectrolytes from a Coarse-Grained Model
نویسندگان
چکیده
منابع مشابه
Complex coacervation of supercharged proteins with polyelectrolytes.
Complexation of proteins with polyelectrolytes or block copolymers can lead to phase separation to generate a coacervate phase or self-assembly of coacervate core micelles. However, many proteins do not coacervate at conditions near neutral pH and physiological ionic strength. Here, protein supercharging is used to systematically explore the effect of protein charge on the complex coacervation ...
متن کاملCoarse graining from coarse-grained descriptions.
We present a generalization of Zwanzig's method of projection operators to the case where the underlying dynamics is not deterministic. The method allows us to perform a coarse graining of an already coarse-grained level of description in which fluctuations are important. The initial level of description is described by a Fokker-Planck equation and, under suitable approximations, the final slow...
متن کاملA coarse-grained model for DNA origami
Modeling tools provide a valuable support for DNA origami design. However, current solutions have limited application for conformational analysis of the designs. In this work we present a tool for a thorough study of DNA origami structure and dynamics. The tool is based on a novel coarse-grained model dedicated to geometry optimization and conformational analysis of DNA origami. We explored the...
متن کاملREVLD: A coarse-grained model for polymers
Article history: Received 15 September 2008 Received in revised form 27 January 2009 Accepted 28 January 2009 Available online xxxx PACS: 61.41.+e 61.25.he 36.20.Ey
متن کاملA Coarse-Grained Protein Model in a Water-like Solvent
Simulations employing an explicit atom description of proteins in solvent can be computationally expensive. On the other hand, coarse-grained protein models in implicit solvent miss essential features of the hydrophobic effect, especially its temperature dependence, and have limited ability to capture the kinetics of protein folding. We propose a free space two-letter protein ("H-P") model in a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Macromolecules
سال: 2018
ISSN: 0024-9297,1520-5835
DOI: 10.1021/acs.macromol.8b00556